Pevesca Plus Capsule 10’S

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PEVESCA PLUS CAPSULE is a combination of Alpha lipoic acid, Methylcobalamin, Folic acid, Pregabalin, and Pyridoxine, which belongs to the group of medicines called Antioxidants, Cyclic GABA analogues, and Vitamin B complexes, respectively. It is used in adults to manage painful diabetic neuropathy (nerve damage occurring over time because of high sugar and fat levels in the blood due to diabetes).

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Alpha Lipoic Acid

ALPHA LIPOIC ACID

Overview:
The potential benefits of alpha-lipoic acid include improving blood sugar in diabetes, relieving nerve pain, promoting weight loss, reducing inflammation, and supporting heart and skin health

Classification: Antioxidant

Uses:

Diabetes and diabetic neuropathy (nerve pain)

Antioxidant support (protects cells from oxidative stress)

Improving skin texture (in anti-aging creams)

Weight loss and metabolism support (though evidence is limited)

Brain health (studied for use in Alzheimer’s and cognitive decline)

Liver support (in conditions like fatty liver disease)

 

How It Works: 

Conversion to EPA & DHA (Partially)

ALA is partially converted in the body into eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA)—the active forms of omega-3s found in fish oil.

This conversion is limited: typically less than 10% of ALA becomes EPA, and even less becomes DHA.

These converted forms play critical roles in anti-inflammatory pathways, brain health, and cardiovascular protection.

Incorporation into Cell Membranes

ALA is integrated into cell membranes, especially in the heart and immune system, improving membrane flexibility and function.

Regulates Inflammation

ALA helps reduce inflammation by affecting the production of pro-inflammatory eicosanoids (signaling molecules).

This can be beneficial in conditions like heart disease, arthritis, and metabolic syndrome.

Lipid Regulation

ALA can lower blood triglycerides and improve cholesterol profiles (increasing HDL and reducing LDL in some studies).

Antioxidant Effects

While not a direct antioxidant, ALA supports antioxidant defenses by modulating gene expression and reducing oxidative stress markers.

Dosage: As prescribed by your doctor.

Side effects:
Low blood sugar
Nausea
Rash (when using an ALA cream or ointment)
Vomiting
Headache
Heartburn

Precautions:
Ask a doctor other healthcare provider before taking ALA if it is safe for you to use this product if you have:
liver disease;
diabetes (Alpha Lipoic Acid can cause low blood sugar);
a thyroid disorder;
a thiamine deficiency (thiamine is a form of vitamin B); or
if you drink large amounts of alcohol.

Disclaimer:
This content is for informational purposes only. Always consult a healthcare provider for medical advice and proper dosage

Methylcobalamin

METHYLCOBALAMIN

Overview

Methylcobalamin is a form of Vitamin B12, a water-soluble vitamin that plays a key role in nerve health, red blood cell production, and DNA synthesis. It’s the active, bioavailable version of B12 used by your body.
Classification
Vitamin B12
Uses
Methylcobalamin is commonly used to:
Treat Vitamin B12 deficiency

Support nerve function and help with conditions like peripheral neuropathy

Manage anemia caused by low B12

Aid in recovery from neurological disorders

Provide support for overall energy and metabolism

It may also be recommended in diabetic neuropathy, sciatica, and neurological pain management.
How It Works
Methylcobalamin works by:
Replenishing low B12 levels, which is crucial for making healthy red blood cells

Helping maintain the myelin sheath, the protective layer around nerves

Assisting in methylation processes – essential for detoxification, DNA repair, and mood regulation

Supporting proper neurological and cognitive function

Unlike other forms of B12 (like cyanocobalamin), methylcobalamin is already active, so the body doesn’t need to convert it to be effective.
Dosage
As prescribed by your doctor.

Side effects
Although generally safe, some people may experience:
Mild diarrhea

Nausea

Headache

Tingling or numbness

Skin rash or itching (rarely)

Allergic reactions, though uncommon

If side effects persist or worsen, it’s best to consult a healthcare provider.
Precautions
Pregnant or breastfeeding women should only use it if prescribed

People with Leber’s disease (a rare eye condition) should avoid B12 supplements

Use cautiously if you have kidney problems or a history of allergies

Let your doctor know about all medications or supplements you’re taking to avoid interactions

Regular monitoring may be needed for long-term use
Disclaimer
This content is for informational purposes only. Always consult a healthcare provider for medical advice and proper dosage

Pregabalin

PREGABALIN

Overview:

Pregabalin is a medicine used to relieve nerve-related pain, prevent seizures, and manage anxiety. It works by calming overactive nerves in the brain and spinal cord, which helps reduce pain, tingling, or abnormal nerve signals. People use it to treat nerve pain from diabetes, lingering pain after shingles, fibromyalgia, or epilepsy.

Classification: Anticonvulsant 

Uses:

Pregabalin is mainly used to relieve nerve-related pain, control seizures, and manage anxiety. It can help with nerve pain caused by diabetes, post-shingles pain, fibromyalgia, or other nerve disorders, making daily life more comfortable. It’s also used as part of epilepsy treatment to help prevent seizures. 

How it works:

Pregabalin can relieve nerve pain by calming those nerves that are overactive in the brain and the spinal cord. It attaches to specific calcium channels on nerve cells thereby lowering transmission of chemical substances that carry the pain signal or induce a seizure. In this manner, Pregabalin decreases nerve pain, tingling of the nerve, and abnormal nerve activity making people more comfortable and in control of their symptoms.

Dosage: As prescribed by your doctor.

Side Effects:

  • Drowsiness or sleepiness
  • Dizziness or lightheadedness
  • Weight gain or mild swelling (edema)
  • Dry mouth
  • Blurred vision

Precautions:

Before taking Pregabalin, it’s important to tell your doctor if you have any kidney problems, heart issues, or a history of mood disorders. Avoid driving or operating heavy machinery until you know how the medicine affects you, because it can cause drowsiness or dizziness. Take it exactly as prescribed and do not stop suddenly, as this can trigger seizures. Also tell your doctor about any other medicines or supplements you use to prevent interactions.

Disclaimer:This content is for informational purposes only. Always consult a healthcare provider for medical advice and proper dosage.

Vitamin B6

VITAMIN B6

Overview

Vitamin B6 is an essential nutrient that your body needs to stay healthy. It plays a big role in keeping your nerves, brain, and blood cells working properly. Since your body can’t make it on its own, you get it from food or supplements

Classification
Vitamin B6 is a water-soluble vitamin, part of the B-complex family. This means it dissolves in water and doesn’t stay stored in the body for long — so you need to take it regularly through diet or supplements.
Uses
Vitamin B6 is used for:
Boosting brain function and mood

Supporting healthy nerves

Forming red blood cells

Helping the body break down proteins and carbs

Relieving nausea during pregnancy

Improving PMS symptoms

Preventing or treating vitamin B6 deficiency
How It Works
Vitamin B6 helps the body:
Make neurotransmitters – chemicals that send messages in the brain

Produce hemoglobin – the part of red blood cells that carries oxygen

Break down food into energy

Keep the immune system strong

In short, it helps your brain, nerves, and metabolism stay in balance.
Dosage
As prescribed by your doctor.

Side effects
Usually safe when taken in normal amounts. But in large doses or long-term use:
Numbness or tingling in hands and feet

Nausea or stomach pain

Sensitivity to sunlight

Tiredness or headache

Nerve damage (very high doses over time)

Precautions
Don’t take high doses for a long time without a doctor’s advice.

Talk to your doctor if you have nerve problems, kidney disease, or are on other medications.

Safe during pregnancy and breastfeeding in recommended doses, but avoid overdosing.

Always follow the label or doctor’s instructions for the correct dosage.
Disclaimer
This content is for informational purposes only. Always consult a healthcare provider for medical advice and proper dosage

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