Leflunomide
LEFLUNOMIDE
Overview:
Leflunomide is a drug that is administered to remedy rheumatoid arthritis and other associated autoimmune diseases. It operates by impairing the immune system thus alleviating joint pain, swelling and progressive destruction. It does not act immediately, so it is time consuming but it can alleviate symptoms as long as one is in practice. It may also interfere with the liver and immune system, which is the reason why frequent check-ups and blood tests are needed when using it.
Classification:Immunomodulatory agent
Uses:
The predominant indication of leflunomide is rheumatoid arthritis where it is employed as well as in the case of psoriatic arthritis. It is useful to alleviate joint pain, swelling, stiffness, and also reduces the pace of long-term damage which could happen because of the conditions. Some cases allow it to be used in other autoimmune diseases in case your physician believes it would suit well.
How it works:
The mechanism of Leflunomide operation is slowing the pace of immune cells which cause redness to autoimmune diseases such as rheumatoid arthritis. It inhibits an enzyme known as DHODH which these immune cells require in order to develop and divide. It reduces swelling, pain, and destruction of the joints since it curbs their excessive activity. It is not an overnight remedy, and, under constant use, it helps quiesce the immune system and regulate the symptoms.
Dosage: As prescribed by your doctor.
Side Effects:
Diarrhea
High blood pressure
Elevated liver enzymes (found in blood tests)
Hair thinning or mild hair loss
Headache
Precautions:Your doctor should be aware of liver problems, previous infection, and immune system preexistence before the beginning of Leflunomide. The drug may have the effect of damaging your liver and reducing the effectiveness of your body to defend against infections and thus you are required to routinely take blood tests. Pregnant women cannot take it and it may remain in your body as long as months hence men and women who want this should control their movements by using birth control. Moreover, one should not drink alcohol, taking it to minimize the possibility of the liver being damaged.
Disclaimer: This content is for informational purposes only. Always consult a healthcare provider for medical advice and proper dosage.
