FUSINOL PLUS Cream 15gm
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FUSINOL PLUS CREAM is a combination of Clobetasol, Fusidic acid, and Clotrimazole which belong to a group of medicines called Topical Corticosteroids, Oral antistaphylococcal antibiotic, and Imidazoles respectively. FUSINOL PLUS CREAM is used in the topical management of a wide variety of bacterial and fungal skin infections with associated inflammation in resistant and/or secondary bacterial infections.
Clobetasol
Clobetasol Propionate 0.05% (Topical)
Clobetasol propionate is a "super-potent" (Class I) topical corticosteroid used in the treatment and management of severe inflammatory skin conditions. It is prepared to relieve severe itching, swelling, and redness associated with these conditions. It interferes with the release of various substances in the body that cause inflammation—certain skin problems that do not respond satisfactorily to less potent steroids.
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Therapeutic Indications
Psoriasis: Helpful in cases of moderately severe lesions of plaque psoriasis (excluding widespread plaque psoriasis).
Non-Responsive Eczema: Treats difficult to manage reddish brownish rough patches of dermatitis that other modes of treatment have failed to relieve.
Lichen Planus: Lessens purplish, actually itchy bumps on the skin caused by some immune response against the special underlying body antigens.
Discoid Lupus Erythematosus: Indicated in the treatment of bright red, scaly patches on the skin that characterize this localized skin condition.
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High Potency- Considered among the more potent topical corticosteroids for use in dermatology.
Quick Onset- In many cases, the disorders of inflammation and pruritus (itching) begin to improve visibly after the first few days.
Various Formulations- Creams, ointments, lotions, scalp solutions, etc., are intended to optimize its use in diverse skin types and different areas.
Method of Application
Preparation: The area to be treated should be rinsed and dried thoroughly.
Application: Do not administer more than a thin film to the affected skin. Gently rub and massage until absorbed.
Frequency: Typically used twice daily-morning and evening. Strictly adhere to the advice given by the dermatologist.
Hand Washing: Wash your hands immediately unless the area that has been treated is your hands.
Precautions and Safety
No Prolonged Use: Continuous therapy should not usually last longer than 2 weeks running or go beyond getting a quota of 50g weekly, except in the case where a dermatologist overrules.
Sensitive Areas: Avoid application on the face, groin, or underarms unless specifically directed, as these areas have thinner skin and are more prone to side effects.
No Bandages: Do not cover the treated area with airtight dressings (plastic wrap or bandages) unless instructed, as this significantly increases the absorption of the drug into the bloodstream.
Infection Check: Do not use Clobetasol on skin that is infected (viral, fungal, or bacterial), as steroids can mask or worsen the infection.
Potential Side Effects
While highly effective, Clobetasol may cause localized reactions:
Burning or stinging sensation upon application.
Thinning of the skin (atrophy).
Appearance of fine blood vessels (telangiectasia).
Stretch marks (striae) or changes in skin color.
Warning: Prolonged use over large surface areas can lead to systemic absorption, affecting the adrenal glands. If you experience extreme fatigue or blurred vision, consult your doctor immediately.
Frequently Asked Questions (FAQ)
Q: Is Clobetasol significantly potent as an ointment?
Yes. Clobetasol is a strong potion that belongs to Category/Super Highs. Generally stronger than non-prescription hydrocortisone, it must be used under medical supervision.
Q: Can I apply Clobetasol for recurring acne of the face?
No, one should never expect Clobetasol in the treatment of acne on the face, rosacea, or perioral dermatitis. Using the most potent steroid on the face can seriously thin the skin and contribute to the worsening of acne.
Q: So can it be used on children?
Not generally. Clobetasol is usually not recommended for children under 12 years. Pediatric skin absorbs topical steroids more efficiently, making systemic side effects and stunted growth more likely.
Q: Could it tackle a fungal ailment like ringworm?
Absolutely not! Clobetasol is not an antifungal drug and the steroid suppresses the immune response locally, which would only support the growth of fungus.
Q: What should be done in cases of a missed dose?
Instill the dose as soon as you remember. If the time is very close for the next dose, then start afresh. Exception is not nullified; go on if the time comes appropriate. Never apply the missed dose twice.
Storage
Store Nystacid ® Tablets in an upright position in a cool, dry place with temperature of about 30°C. Avoid freezing. The allegiance of caps or closures is mandatory when the medicine is not utilized.
Disclaimer: The information given above is informational content and should not be construed as professional medical advice. Always apply this medicine as per your doctor’s prescription.
Clotrimazole
Clotrimazole Topical Solution / Cream
Clotrimazole belongs to the imidazole class of antifungal drugs and is widely regarded as a gold-standard treatment for fungal skin infections. It works by inhibiting ergosterol synthesis, an essential component of the fungal cell membrane, thereby disrupting fungal growth and eliminating infection.
Treatment Indications
Athlete’s Foot (Tinea Pedis): Relieves itching, burning, and cracks between toes
Ringworm (Tinea Corporis): Clears circular, red, scaly lesions
Jock Itch (Tinea Cruris): Treats infections in groin and inner thighs
Thrush: Effective for yeast infections on the skin
Candidiasis: Used for diaper rash and skin fold infections
Pityriasis Versicolor: Treats skin discoloration patches
Features
Quick Relief: Reduces itching, redness, and irritation rapidly
Multiple Forms: Available as cream, lotion, and powder
Safe Profile: Generally safe for all age groups under guidance
How to Apply
Preparation: Clean and dry the affected area thoroughly
Application: Apply a thin layer extending ~1 cm beyond infected skin
Frequency: Usually 2–3 times daily for 2–4 weeks
Continuation: Continue treatment even after symptoms improve to prevent recurrence
Safety Instructions
External Use Only: Avoid contact with eyes, nose, and mouth
Skin Reactions: Mild stinging or redness may occur
Pregnancy/Breastfeeding: Use under medical supervision
Hygiene: Change towels and socks daily to prevent reinfection
Frequently Asked Questions (FAQs)
Q: How long does it take to work?
Relief starts within 48–72 hours, with visible healing in 1–2 weeks
Q: Can it be used for vaginal infections?
Use only formulations labeled for vaginal use
Q: Is it safe for babies?
Yes, commonly used for diaper rash (candidiasis) with care
Q: What if I miss a dose?
Apply when remembered; do not double apply
Q: Can I cover the area after applying?
Avoid covering unless advised; air exposure aids healing
Fusidic Acid
Fusidic Acid 2% w/w Cream/Ointment
Fusidic Acid is an effective topical bactericidal antibiotic used to treat a variety of bacterial skin infections. It is particularly active against Staphylococcus species, including resistant strains. It works by inhibiting bacterial protein synthesis, thereby stopping the spread of infection and promoting skin healing.
Therapeutic Uses
Impetigo: Treats honey-crusted skin lesions
Infected Dermatitis: Manages secondary infections in eczema or psoriasis
Folliculitis: Reduces infection and inflammation of hair follicles
Infected Wounds: Helps treat minor cuts, scrapes, and stitches
Erythrasma: Effective for bacterial infections in skin folds
Key Benefits
Targeted Action: Works mainly against Gram-positive bacteria
Deep Penetration: Reaches infection beneath the skin surface
Low Irritation: Generally well-tolerated, even in sensitive areas
How to Apply
Hand Hygiene: Wash hands before and after application
Clean Area: Gently cleanse with mild soap
Application: Apply a thin layer to the affected area
Frequency: Usually 3–4 times daily or as directed
Duration: Continue for 7–14 days or as prescribed
Possible Adverse Reactions
Mild burning or stinging sensation
Redness or itching (contact dermatitis)
Rare: Skin rash, hives, or severe allergic reaction
Precautions and Warnings
Avoid Eyes: Rinse immediately if accidental contact occurs
Antibiotic Resistance: Avoid misuse for non-bacterial infections
Pregnancy/Breastfeeding: Use under medical advice, especially near breast area
Hygiene: Do not share medication to prevent cross-contamination
Frequently Asked Questions (FAQs)
Q: Is it a steroid cream?
No, it is a pure antibiotic (some combinations may include steroids)
Q: Can it be used for acne?
Not first-line; better for infected lesions or boils
Q: How long does it take to work?
Improvement usually seen in 48–72 hours
Q: Can I cover the area?
Yes, covering may help better absorption
Q: Difference between cream and ointment?
Cream suits moist infections, ointment suits dry or crusty areas
At Gem Pharmacy, we make every effort to provide accurate, expert-written, and thoroughly reviewed information related to medicines. However, this information should not be considered a substitute for professional medical advice, diagnosis, or treatment from a qualified doctor.
The purpose of this information is to educate users and improve communication between patients and healthcare professionals. It should not be used to diagnose or treat any condition.
Always consult a certified healthcare professional before taking any medication.










