Ceftriaxone
CEFTRIAXONE
Overview:
Ceftriaxone is a third-generation cephalosporin antibiotic that kills bacteria by blocking their cell wall formation. It is used to treat a wide range of serious bacterial infections, including pneumonia, meningitis, urinary tract infections, and skin or bone infections. It is usually given as an injection or IV and should be used under medical supervision.
Classification: Cephalosporin antibiotics
Uses:
- Treats pneumonia and respiratory tract infections
- Used for urinary tract infections
- Treats blood infections (sepsis) and meningitis
- Helps with skin, bone, and joint infections
- Effective in sexually transmitted infections like gonorrhea
- Used for intra-abdominal infections and other serious bacterial infections
How it works:
Ceftriaxone is a β-lactam antibiotic that works by binding to bacterial enzymes called penicillin-binding proteins (PBPs). This blocks the final step of bacterial cell wall synthesis, causing the wall to weaken and rupture. As a result, the bacteria die, making it a bactericidal antibiotic.
Dosage: As prescribed by your doctor.
Side Effects:
- Allergic reactions – rash, itching, or hives
- Gastrointestinal issues – nausea, vomiting, diarrhea, stomach upset
- Injection site reactions – pain, redness, or swelling
- Changes in blood – temporary low white blood cells or platelets in some cases
- Liver or kidney effects – rare, may affect liver enzymes or kidney function
Precautions:
Ceftriaxone is a strong antibiotic, but it needs to be used carefully. People who are allergic to penicillin or cephalosporins should avoid it. If you have kidney or liver problems, your doctor may adjust the dose. It should be used cautiously in newborns, infants, pregnant, or breastfeeding women. Also, it shouldn’t be mixed with calcium IV solutions, and if you notice persistent diarrhea, you should tell your doctor right away.
Disclaimer:This content is for informational purposes only. Always consult a healthcare provider for medical advice and proper dosage.
Tazobactam
TAZOBACTAM
Overview:
Tazobactam is a β-lactamase inhibitor that enhances the effectiveness of β-lactam antibiotics such as piperacillin. It works by blocking bacterial β-lactamase enzymes, which are produced by bacteria to inactivate antibiotics. By doing so, Tazobactam protects the antibiotic, allowing it to kill bacteria efficiently, and is commonly used in treating serious infections like pneumonia, urinary tract infections, skin infections, and intra-abdominal infections.
Classification: β-lactamase inhibitor
Uses:
Tazobactam is used to boost the effect of antibiotics, helping them fight bacteria more effectively. It is commonly combined with medicines like piperacillin to treat serious infections such as pneumonia, urinary tract infections, skin infections, and infections inside the abdomen. By neutralizing bacterial resistance mechanisms, it enables antibiotics to kill bacteria faster, supporting a smoother recovery.
How it works:
Tazobactam is a β-lactamase inhibitor that binds to and inactivates bacterial β-lactamase enzymes, which are produced by certain bacteria to destroy β-lactam antibiotics. By inactivating these enzymes, Tazobactam shields the antibiotic from degradation, allowing it to target PBPs and hinder bacterial cell wall development.This results in effective bacterial killing and resolution of the infection.
Dosage: As prescribed by your doctor.
Side Effects:
- Nausea
- Vomiting
- Diarrhea
- Stomach pain or discomfort
- Headache
Precautions:
Before taking Tazobactam, make sure you aren’t allergic to it or similar antibiotics like piperacillin. If you have kidney or liver problems, your doctor may adjust your dose. Pregnant or breastfeeding women should use it only under medical supervision. Always tell your doctor about other medicines you’re taking, and be alert for allergic reactions such as rash, swelling, or trouble breathing, which need immediate attention.
Disclaimer:This content is for informational purposes only. Always consult a healthcare provider for medical advice and proper dosage.
