Nimesulide
Nimesulide
OVERVIEW
Nimesulide is a non-steroidal anti-inflammatory drug (NSAID) primarily used for pain relief, inflammation reduction, and fever management
CLASSIFICATION
Anti-inflammatory drug (NSAID)
USES
Nimesulide is a non-steroidal anti-inflammatory drug (NSAID) commonly used for pain relief and fever reduction. It helps manage acute pain, menstrual cramps (dysmenorrhea), back pain, Nimesulide is also effective in treating dental pain caused by nerve damage, infection, decay, extraction, or injury.
HOW IT WORKS
Nimesulide inhibits the COX-2 enzyme, which plays a crucial role in the production of prostaglandins. Prostaglandins are chemicals in the body that promote inflammation, pain, and fever.
DOSAGE
As directed by the physician
PRECAUTIONS
Take it with food or milk to prevent an upset stomach.
Take it as per the dose and duration prescribed by your doctor. Long term use may lead to serious complications such as stomach bleeding and kidney problems.
Inform your doctor if you have a history of heart disease or stroke.
Avoid consuming alcohol while taking Nimesulide as it can increase your risk of stomach problems.
Your doctor may regularly monitor your kidney function, liver function and levels of blood components if you are taking this medicine for long-term treatment.
SIDE EFFECTS
Acid or sour stomach
Stomach discomfort and cramps
Dizziness
Skin rash
Nausea and Vomiting
Elevated Liver enzymes
Blood clotting disorders
Diarrhea
DISCLAIMER
This content is for informational purposes only. Always consult a healthcare provider for medical advice and proper dosage.
Paracetamol
PARACETAMOL
Overview
Paracetamol is a commonly used medication that helps relieve mild to moderate pain and reduce fever. It’s often used for:
Headaches
Toothaches
Muscle and back pain
Menstrual cramps
Cold and flu symptoms
It’s available over-the-counter and is considered safe when used as directed.
Classification
Analgesic and antipyretic agent
Uses
Paracetamol is used for pain relief and fever. It is used to relieve pain in conditions like headache, muscle pain, or dental pain.
How it works
When you produce a fever, your body’s internal thermostat — found in the hypothalamus portion of the brain — is raised to a higher temperature. This new set point is usually induced by pyrogens (substances made during infections) that tell the body to produce more heat as a form of immune defense.
Due to its effects in the brain, paracetamol reduces the production of reactive prostaglandins. Prostaglandins are disease-fighting chemicals released during infection that in turn, raise the body’s temperature set point. By decreasing prostaglandin levels, paracetamol enables the hypothalamus’ temperature control centre to bring the body’s temperature back down to normal, allowing the body to cool down and the fever to subside
Dosage
As directed by the physician
Precautions
Most people can take paracetamol safely, including:
pregnant women
breastfeeding women
children over 2 months of age – lower doses are recommended for young children
always get advice before taking paracetamol if you:
have liver or kidney problems
have problems with alcohol, like long-term alcohol misuse
are very underweight
are taking other medications
Don’t take paracetamol if you’ve had an allergic reaction to it in the past
Side effects
common side effects of paracetamol.
Nausea
Swelling
Vomiting
Pain
Tenderness in the upper abdomen
Sweating
Loss of appetite
Stomach cramps
Diarrhea
Major side effects are as follows:
Dark-colored urine
High fever
Lower backache
Skin having red spots
Rashes
Inflammation
Itching
Sore throat
Ulcers
Breathlessness
Yellowish eyes
Disclaimer
This content is for informational purposes only. Always consult a healthcare provider for medical advice and proper dosage.
