BACITRACIN ZINC
Overview:
Bacitracin zinc is an antibiotic used mainly in ointments and creams to prevent or treat minor skin infections, cuts, and burns. The zinc is added to stabilize bacitracin and make it more effective for topical use. It works by stopping bacteria from building their cell walls, which kills or prevents their growth. Since it’s only for external use, it’s generally safe, but some people may develop skin irritation or allergies.
Classification: Polypeptide antibiotic
Uses:
Bacitracin zinc is commonly used in ointments and creams to protect small cuts, scrapes, and burns from getting infected. It works as a first-aid antibiotic that helps wounds heal safely, and is often combined with other antibiotics like neomycin or polymyxin B for broader protection. Doctors also use it to lower the risk of infection after minor surgeries or skin injuries.
How it works:
Bacitracin zinc acts by inhibiting bacterial cell wall synthesis.It complexes with bactoprenol pyrophosphate and inhibits its regeneration, preventing the translocation of peptidoglycan subunits through the cytoplasmic membrane. This interruption in peptidoglycan biosynthesis results in a weakened bacterial cell wall and ultimately cell lysis.
Dosage: As prescribed by your doctor.
Side Effects:
- Mild skin irritation
- Redness at the site of application
- Itching
- Rash
Precautions:
Bacitracin zinc should only be applied on the skin and not near the eyes, mouth, or deep cuts. It’s best used for small wounds, since applying it on large or serious injuries should only be done under a doctor’s advice. Prolonged use isn’t recommended because it can lead to resistant bacteria or fungal growth. If you notice redness, itching, or swelling, you may be allergic and should stop using it. Pregnant or breastfeeding women, as well as children and elderly patients, should use it cautiously and only if prescribed.
Disclaimer:This content is for informational purposes only. Always consult a healthcare provider for medical advice and proper dosage.