CHLORTHALIDONE

Overview:

Chlorthalidone is a “water pill” that helps your body get rid of extra salt and water through urine. It’s mainly used to lower high blood pressure and reduce swelling from heart, kidney, or liver problems.By flushing out extra fluid, it reduces pressure on the heart and arteries.It comes as a tablet and should be taken under a doctor’s guidance to keep your blood pressure and electrolytes in check.

Classification: Sulfamoylbenzamide

Uses:

Lowers high blood pressure (hypertension) to protect the heart and blood vessels

Helps prevent fluid buildup that can make the heart work harder

Reduces swelling (edema) caused by heart, kidney, or liver problems

Can be used to help balance electrolytes with proper medical supervision.

How it works:

Chlorthalidone is a thiazide-like diuretic that acts on the distal convoluted tubules of the nephron. It inhibits the Na⁺/Cl⁻ symporter, reducing sodium and chloride reabsorption. By removing sodium, chloride, and water, it decreases the amount of fluid in the blood, lightens the heart’s workload, and reduces blood pressure.

Dosage: As prescribed by your doctor.

Side Effects:

Increased urination – may lead to dehydration if fluids aren’t replaced

Low potassium (hypokalemia) –can cause weakness, cramps, or irregular heartbeat

Low sodium (hyponatremia) – may cause fatigue, headache, or confusion

High uric acid (hyperuricemia) – can trigger gout in susceptible people

Low magnesium (hypomagnesemia) – may lead to muscle cramps or weakness

Precautions:

Chlorthalidone helps lower blood pressure and reduce swelling but should be used carefully. Avoid it if you’re allergic, and people with kidney or liver problems should be cautious. Monitor electrolytes, blood sugar, and uric acid, as it can cause dizziness or lightheadedness, especially when standing up. Pregnant or breastfeeding women should use it only under a doctor’s guidance.

Disclaimer:This content is for informational purposes only. Always consult a healthcare provider for medical advice and proper dosage.