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PHENYLEPHRINE HYDROCHLORIDE

Overview

Phenylephrine is a nasal decongestant used to temporarily relieve nasal discomfort caused by colds, allergies, and hay fever. It works by reducing swelling in the nasal passages, making it easier to breathe. However, it does not address the underlying cause of the symptoms or speed up recovery

Classification
Nasal decongestants

Uses

Oral and nasal phenylephrine are used as nasal decongestants to temporarily unblock a nose or relieve sinus pressure in people with nasal and sinus congestion caused by colds, allergies, or hay fever. While phenylephrine can provide some symptom relief, it doesn’t treat the underlying cause or speed recovery

How it works

Phenylephrine Hydrochloride is a sympathomimetic amine used as a topical decongestant, systolic vasopressor, and mydriatic agent. Its mechanism of action works through various pathways with the mechanism of action primarily based on its ability to stimulate alpha-adrenergic receptors, particularly alpha-1 receptors, which are involved in vascular smooth muscle contraction.

Dosage

As directed by the physician

Precautions

Before using Vazculep, please note:

Allergies: If you’re allergic to phenylephrine or any of its ingredients, avoid using this medication.

Children: Keep this medication out of reach of children. In case of overdose, seek medical help or contact a Poison Control Center immediately.

Contraindications (Do not use if you have):

Severe high blood pressure (hypertension)

Ventricular tachycardia (a type of rapid heart rate)

Closed-angle glaucoma (a condition affecting the eyes)

Hypersensitivity to phenylephrine or sulfites (a type of preservative)

Use with caution if you have:

Heart or blood vessel problems

Thyroid issues

Diabetes

Enlarged prostate

Liver or kidney problems

Asthma or sulfite sensitivity

Pregnancy & Breastfeeding:

Use during pregnancy only if the potential benefit justifies the potential risk to the fetus.

Considered safe during breastfeeding, but consult your doctor.

Side effects

Injection Site Reactions: Leakage of intravenous medication

Cardiovascular: High blood pressure (hypertension)

Heart Rate: Slow heart rate (bradycardia)

Mental Health: Anxiety, nervousness, restlessness

Neurological: Headache, dizziness, lightheadedness

Respiratory: Shortness of breath, chest tightness, wheezing

Gastrointestinal: Nausea, stomach pain or upset

Renal: Reduced urine output, decreased blood flow to the kidneys

Pulmonary: Fluid accumulation in the lungs (pulmonary edema)

Rebound Symptoms: Nasal congestion worsening after initial relief (rebound congestion)

Skin: Burning or stinging sensation

Other: Sneezing

If you experience any of these side effects, it’s important to consult with a healthcare professional for guidance.

Disclaimer

This content is for informational purposes only. Always consult a healthcare provider for medical advice and proper dosage.

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