Rimegepant: The Dual-Action Innovation in Migraine Care
A migraine is more than just a headache; it is a debilitating neurological event. Rimegepant is a cutting-edge, orally disintegrating tablet (ODT) designed to target the root cause of migraine pain. It is the first medication in its class approved for both the acute treatment of a migraine as it happens and the preventative treatment of episodic migraines.
Rimegepant blocks the Calcitonin Gene-Related Peptide (CGRP) receptor which transmits pain signals through its specific protein blocking mechanism that protects users from most side effects found in traditional triptans and older preventive medications.
The tablet uses Rapid Dissolve Technology to dissolve on the tongue because it requires no water for patients who experience nausea or vomiting during an attack. The Dual-Purpose Therapy system enables users to stop their active migraine while their every-other-day treatment reduces monthly migraine days.
Rimegepant provides an essential alternative treatment because it avoids blood vessel constriction which triptans use to treat patients who have cardiovascular risk factors. A single dose can provide sustained pain freedom for up to 48 hours for many individuals.
Product Overview & Usage
Feature
Details
Drug Class
CGRP Receptor Antagonist (Gepant)
Common Uses
Acute migraine with/without aura; Episodic migraine prophylaxis
Administration
Place on or under the tongue; let it dissolve completely
Dosing (Acute)
75 mg as needed (Max 1 dose in 24 hours)
Dosing (Preventive)
75 mg every other day
Rimegepant provides a different treatment method than traditional triptans which use blood vessel narrowing to relieve pain. Rimegepant takes a different route because it blocks the CGRP receptor which activates both the inflammation and pain signals. The treatment provides relief to patients because it does not cause “chest tightness” and blood vessel constriction.