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TACROLIMUS
Overview:Tacrolimus is an immunosuppressant medicine that relieves the skin inflammation, which occurs in eczema. It has an immunosuppressive mechanism of action. It is also applied to avoid rejection of the organs when being transplanted. It has typical side effects that comprise burning or itching and intake is not supposed to be exposed to sunlight.
Classification: Calcineurin inhibitor
Uses:Tacrolimus is used in the treatment of moderate to severe atopic dermatitis (eczema) to minimize skin inflammation and the immune system primarily when other standard interventions such as steroids are inappropriate. It stops the rejection of organs when a person is transplanted (as an oral or injectable drug) by suppressing the immune system and is employed in the prevention of heart, liver, or kidney rejection.
How It Works:Tacrolimus prevents the activation of T-cells through the inhibition of the protein known as calcineurin that is required to activate T-cells that form an important component of the immune system. Tacrolimus can inhibit cytokines and the formation of cytokines that fuel inflammation, in particular interleukin-2 (IL-2), by the inhibition of calcineurin. This is useful in treating skin ailments such as eczema and the prevention of rejections of organs that had been transplanted.
Dosage:
As prescribed by your doctor.
Side Effects:
- Burning or stinging sensation at the application site
- Itching or redness
- Skin sensitivity, especially to sunlight
- Mild irritation
Precautions:
If you’re using Tacrolimus, avoid too much sunlight, as it can make your skin more sensitive. Apply it only on healthy skin, not on cuts or infections, and wash your hands after use. Don’t use it for too long unless your doctor says so. It’s not meant for children under 2, and if you’re pregnant or breastfeeding, talk to your doctor first.
Disclaimer:This content is for informational purposes only. Always consult a healthcare provider for medical advice and proper dosage.