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This combination is used to relieve symptoms of allergic rhinitis and improve breathing by blocking both histamine and leukotriene pathways
Bilastine
Bilastine 20mg Tablet
Bilastine is a potent and long-acting peripherally selective H1-receptor antagonist. It belongs to the second generation of antihistamines and is specially formulated for rapid relief of allergy symptoms, such as allergic rhino-conjunctivitis and urticaria (hives). Unlike traditional antihistamines, the drug reaches the brain minimally to give relief to the patient without inducing daytime drowsiness.
Indications
Allergic Rhinitis: This medicine best relieves sneezing, itching, and runny or blocked nose caused by seasonal (hay fever) or perennial allergic rhinitis.
Allergic Conjunctivitis: This medicine alleviates the congestion, itchy redness, and watery discharge of eyes.
Urticaria (Hives): It treats cutaneous rashes, wheals, and pruritic spots blitzing chronic idiopathic urticaria.
Dust & Pollen Allergy: This 24-hour therapy targets the environmental exposures that could threaten your calm life.
Main Benefits
Non-Sedating Formula: It does not affect the central nervous system and enables you to keep awake during your daily work or driving.
Quick Onset: Onset of action is seen in 30–60 minutes.
Time of Once-Daily Dosing: A 20mg dosage is to be taken once a day for 24-hour relief.
High Safety Profile: Safe to use; usually does not cause anticholinergic side-effects (like dry mouth) as older antihistamines do.
Dosage & Administration
General Dose: For adults and children aged more than 12 years, a regular 20mg dose is taken once in a day.
One-Hour Rule: Bilastine must be taken on an empty stomach. It should be taken one hour before or 2 hours after food or fruit juice to preserve the therapeutic adequacy.
Method: Swallow the tablet whole with water.
Adverse Effects
While most people do not experience adverse effects, some mild symptoms may be seen:
Intermittent headache or dizziness
Mild stomach discomfort
Fatigue (rarely)
Warning: Seek immediate emergency help if you exhibit any signs of very rare allergic reactions, such as swelling of the face, lips, or tongue, or difficulty in breathing.
Precautions & Interactions
Interaction with Food & Juice: Do not combine this medicine with grapefruit juice or any other fruit juices because they seriously dampen the intake of Bilastine.
Kidney Health: Patients with moderate to severe renal function should be seen by their doctor as Bilastine may require dose adjustments or special monitoring.
Use of Alcohol: While Bilastine does not significantly magnify the effects of alcohol, it is best not to consume alcohol while taking this drug.
Pregnancy: Talk to your healthcare provider before taking this drug if you are pregnant, planning to conceive, or breastfeed.
Frequently Asked Questions (FAQs)
Q: How does Bilastine compare to other antihistamines like Cetirizine or Levocetirizine?
Considering all are effective antihistamines, Bilastine has the least rate of causing sedation while compared to the others in the group, and therefore is preferred by many patients during the day compared to Cetirizine.
Q: Why do I have to take it on an empty stomach?
Food, especially fatty meals and fruit juices, significantly reduces the bioavailability of Bilastine up to 30%. Thus, it essentially ensures that the greatest possible absorption of Bilastine is possible.
Q: Can Bilastine be taken for the common cold?
Antihistamines like Bilastine are mainly used in cases of generalized allergies. If they have a runny nose from an allergic symptom, then their effect on virus-related common cold symptoms is minimal.
Q: For how long can I take Bilastine?
The duration of treatment depends on the intensity of your symptoms. For seasonal affectation, you would take the drug during the period of maximal exposure; for ongoing conditions like urticaria; you may be advised to take it for longer. Always stay updated regarding the advice provided by your qualified practitioner.
Q: Does taking this make me gain weight?
There is no evidence linking Bilastine to any weight gain, which is common with some older antihistamines.
Montelukast
Montelukast 10mg Tablet
Montelukast is a bioactive molecule belonging to the class of Leukotriene Receptor Antagonists (LTRAs). It is widely used for long-term management of asthma and allergic rhinitis.
Unlike rescue inhalers, Montelukast works by blocking leukotrienes—natural chemicals that cause airway inflammation, swelling, and tightening. This helps keep the airways open and improves breathing over time.
Main Applications
Asthma Prevention: Helps reduce the frequency and severity of asthma attacks in both children and adults.
Allergic Rhinitis: Relieves sneezing, runny nose, and itchy eyes caused by seasonal or perennial allergies.
Exercise-Induced Bronchospasm: Prevents chest tightness during or after physical activity.
Alternative to Steroids: Often used in patients who cannot tolerate inhaled corticosteroids or prefer alternatives.
How to Use Montelukast
Night Dose: For asthma or combined asthma-allergy treatment, it is best taken once daily in the evening.
Allergy Alone: When used only for allergies, timing may vary, but consistency is important.
Before Exercise: For exercise-induced asthma, take a dose about 2 hours before activity. Do not take extra doses if already on daily therapy.
Long-Term Use: This is a preventive medicine and should be taken regularly, even if symptoms improve.
Precaution
Mood Changes Warning: Some patients (especially children) may experience behavioral or mood changes such as irritability, anxiety, or vivid dreams. Report any unusual symptoms to your doctor immediately.
Not for Acute Attacks: Montelukast does not relieve sudden asthma attacks. Always keep a rescue inhaler (e.g., Salbutamol or Albuterol) for emergencies.
Aspirin Sensitivity: Avoid aspirin and NSAIDs (like Ibuprofen) if they trigger your asthma.
Liver Consideration: Inform your doctor about any liver disease, as the drug is metabolized in the liver.
Some Common Side Effects
Most side effects are mild and temporary:
Mild headache
Abdominal pain or indigestion
Fever or flu-like symptoms (more common in children)
Dizziness or drowsiness
Frequently Asked Questions (FAQs)
Q: Is Montelukast a steroid?
A: No, it is not a steroid. It belongs to the class of leukotriene receptor antagonists and is often used alongside or as an alternative to steroids.
Q: How soon does it start working?
A: Some improvement may be seen within 24 hours, but full benefits usually appear after 1–2 weeks of regular use.
Q: Can children take Montelukast?
A: Yes. It is available in chewable tablets (4 mg, 5 mg) and oral granules for children, but should be used under pediatric supervision.
Q: Can I drink alcohol while taking it?
A: There is no major interaction, but alcohol may increase drowsiness in some individuals. Use caution.
Q: Is it safe during pregnancy?
A: It is generally considered safe if prescribed, but always consult your doctor before starting treatment during pregnancy.
At Gem Pharmacy, we make every effort to provide accurate, expert-written, and thoroughly reviewed information related to medicines. However, this information should not be considered a substitute for professional medical advice, diagnosis, or treatment from a qualified doctor.
The purpose of this information is to educate users and improve communication between patients and healthcare professionals. It should not be used to diagnose or treat any condition.
Always consult a certified healthcare professional before taking any medication.
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