Itraconazole
ITRACONAZOLE
Overview:
Itraconazole is an antifungal medication to treat multiple fungal parasites in the body. It acts by arresting the growth of fungi and is regularly used in the treatment of infections that affect the skin, nails, mouth, throat and lungs. This drug has especially potent effects against yeast like Candida and molds like Aspergillus. Ranging in types in capsules, tablets, and oral solutions, itraconazole has to be used exactly as a provider prescribes.
Classification:Triazole derivative
Uses:
Itraconazole is a drug used in treating various fungus diseases, both skin ones (e.g. ringworm) as well as nail ones (e.g. nail infection like onychomycosis, oral thrush fungal infection and systemic fungal infection like aspergillosis, histoplasmosis and blastomycosis). It is used by inhibiting the growth of the fungus thus helping the body to clear the infection. The drug is specifically used when the infections are either severe or resistant to other antifungal drugs.
How it works:
Itraconazole acts by inhibiting an enzyme that is essential in the synthesis of ergosterol, an essential constituent of fungal cell membrane called lanosterol 14 alpha-demethylase. Lack of ergosterol makes the fungal cell membrane weak and permeable which leads to death of the fungus. This mechanism stops the growth as well as spreading of the fungal infection throughout the body.
Dosage:As prescribed by your doctor.
Side effects:
Nausea
Stomach pain
Vomiting
Dizziness
Diarrhea
Precaution:
Before using itraconazole, be sure to inform your doctor about the occurrence of liver, heart, or kidney diseases in the past. It is important not to combine this medication with other drugs, especially those provided to treat heart or cholesterol disease since there is an increased safety risk. Avoid drinking when on itraconazole since this increases the risk of liver toxicity. Pregnant women and those nursing should never use it unless really necessary and it has been prescribed by the physician. It should also be administered with food and followed carefully as recommended.
Disclaimer:
This content is for informational purposes only. Always consult a healthcare provider for medical advice and proper dosage.
Ofloxacin
OFLOXACIN
OVERVIEW
Ofloxacin is used in the treatment of bacterial infections. It is also used in infections of urinary tract, gastrointestinal tract, female genital organ, skin & soft tissues and lungs (pneumonia).
CLASSIFICATION:
Ofloxacin is an antimicrobial drug in the fluoroquinolone family
USES:
Ofloxacin is a broad-spectrum antibacterial agent with activity against both gram-negative and gram-positive organisms, used for the treatment of bacterial infections such as pneumonia, pyelonephritis, skin and soft tissue infections, and urinary tract infections.
HOW IT WORKS
Ofloxacin acts on DNA gyrase and toposiomerase IV, enzymes which, like human topoisomerase, prevents the excessive supercoiling of DNA during replication or transcription. By inhibiting their function, the drug thereby inhibits normal cell division.
DOSAGE
As directed by the physician
PRECAUTIONS
You should be cautious in the following conditions if you are prescribed Ofloxacin:
Allergic to the medicine or other quinolone/fluoroquinolone antibiotics like Ciprofloxacin, Gemifloxacin, Levofloxacin, etc.
Taking any other medications, vitamins, nutritional supplements, or herbal products.
Taking blood thinners like warfarin, antidepressants, antipsychotics, insulin, and other medicines to treat diabetes like glimepiride, chlorpropamide, tolazamide, etc., and anti-inflammatory drugs like ibuprofen
Taking antacids, supplements, and multivitamins with iron and zinc, then take ofloxacin 2 hours before or 2 hours after taking these medicines.
Medical history of heart diseases or prolonged QT intervals
Pregnancy, breastfeeding, or planning to get pregnant
History of diabetes, hypoglycaemia (low blood sugar) or liver disease
SIDE EFFECTS
The side effects of ofloxacin are:
Fever
Fatigue
Nausea
Constipation
Vomiting
Pale skin
Mouth dryness
Watery stools and maybe blood
Stomach cramps for months, even after the treatment is complete
Itching and rashes
Swelling or yellowing of the eyes and face
Breathing or swallowing trouble
Fluttering heartbeat
Frequent urination and sweating
Constantly feeling hungry or thirsty
If you find any of these symptoms, you should immediately consult your doctor.
Disclaimer
This content is for informational purposes only. Always consult a healthcare provider for medical advice and proper dosage
Ornidazole
ORNIDAZOLE
Overview:
Ornidazole is an antibiotic used to treat infections caused by certain bacteria and parasites. It works by stopping the growth of these microorganisms, helping the body fight infections like intestinal infections, gynecological infections, and some dental or skin infections. It is usually easy to take, though mild digestive issues or a metallic taste may occur in some cases.
Classification: Nitroimidazole derivative
Uses:
Ornidazole is used to treat infections caused by certain bacteria and parasites, such as intestinal infections, gynecological infections, dental infections, and some skin infections. It helps the body fight off these germs and recover faster.Sometimes used for prevention of infections in surgical procedures.
How it works:
Ornidazole works by targeting and stopping the growth of certain bacteria and parasites that cause infections. It interferes with their DNA, preventing them from multiplying, which helps the body clear the infection.In easy terms, it blocks harmful microorganisms from growing, allowing your body to fight off the infection.
Dosage:
As prescribed by your doctor.
Side Effects:
- Nausea or vomiting
- Stomach upset or mild abdominal pain
- Metallic or bitter taste in the mouth
- Headache or dizziness
- Allergic reactions
Precautions:
When using Ornidazole, always take it exactly as prescribed and do not skip doses, even if you feel better. Avoid drinking alcohol while on this medicine, as it can lead to unwanted side effects like nausea or dizziness. Inform your doctor about any liver problems, nerve issues, or if you are pregnant or breastfeeding, so the treatment stays safe and effective for you.
Disclaimer:This content is for informational purposes only. Always consult a healthcare provider for medical advice and proper dosage.
