Bempedoic Acid
BEMPEDOIC ACID
Overview:
Bempedoic acid is a medicine that helps lower “bad” cholesterol in your blood. It works by slowing down your liver’s cholesterol production. People who struggle with statins or need a little extra help take it, and it’s gentler on the muscles than many other cholesterol medicines.
Classification: ATP-citrate lyase (ACL) inhibitor
Uses:
- Helps lower “bad” LDL cholesterol in the blood.
- Treats primary high cholesterol (hypercholesterolemia).
- Helps people with genetic high cholesterol (heterozygous familial hypercholesterolemia).
- Can be added to other cholesterol medicines if more lowering is needed.
- A good option for those who can’t tolerate statins.
How it works:
Bempedoic acid works by slowing down your liver’s cholesterol production. It blocks an enzyme called ATP citrate lyase (ACL), which is part of the pathway your liver uses to make cholesterol. With less cholesterol being made, your body removes more LDL (“bad”) cholesterol from the blood, helping to keep your arteries healthier.
Dosage:As prescribed by your doctor.
Side Effects:
- Muscle aches or pains (usually mild)
- Increased uric acid (may trigger gout in some people)
- Digestive discomfort like stomach upset, constipation, or nausea
- Elevated liver enzymes (usually detected in blood tests)
Precautions:
Before taking Bempedoic acid, it’s important to make sure your liver is healthy and to keep an eye on it during treatment. If you’ve had gout before, watch for flare-ups because it can raise uric acid levels. Pregnant or breastfeeding women should talk to their doctor first. Make sure to tell your doctor about all the medicines you’re taking, since some could interact. Finally, even though muscle problems are less common than with statins, report any unusual aches or weakness right away.
Disclaimer:This content is for informational purposes only. Always consult a healthcare provider for medical advice and proper dosage.
Rosuvastatin
ROSUVASTATIN
Overview:
Rosuvastatin is a medication used to lower “bad” cholesterol (LDL) and triglycerides in the blood while raising “good” cholesterol (HDL). It helps reduce the risk of heart disease, stroke, and other cardiovascular problems—especially in people with risk factors like diabetes, high blood pressure, or a family history of heart disease.
Classification:
Statins (also called HMG-CoA reductase inhibitors)
Uses:
To lower high cholesterol (hyperlipidemia)
To prevent heart attack or stroke
To treat certain inherited cholesterol disorders (like familial hypercholesterolemia)
Often used as part of a heart-healthy plan that includes diet, exercise, and weight control
How It Work:
Rosuvastatin works by blocking an enzyme in your liver that helps make cholesterol. With less cholesterol being made, your body pulls cholesterol out of the blood, lowering overall levels. It also helps stabilize plaque in blood vessels, reducing the risk of heart attacks.
Dosage:
As prescribed by your doctor.
Side Effects:
Most people tolerate rosuvastatin well, but some may experience:
Muscle pain or weakness
Headache
Abdominal pain
Nausea
Elevated liver enzymes (your doctor may monitor this)
Serious but rare:
Severe muscle problems (rhabdomyolysis)
Liver damage
Tell your doctor if you experience unusual fatigue, dark urine, or yellowing of the skin/eyes.
Precautions:
Tell your doctor if you have liver disease, kidney problems, or thyroid disorders.
Avoid excessive alcohol—it increases the risk of liver damage.
Not usually recommended during pregnancy or breastfeeding.
Report any unexplained muscle pain, tenderness, or weakness, especially if accompanied by fever or fatigue.
Let your doctor know about all medications and supplements you’re taking, including over-the-counter products.
Disclaimer:
This content is for informational purposes only. Always consult a healthcare provider for medical advice and proper dosage
