Dapagliflozin
DAPAGLIFLOZIN
Overview
Dapagliflozin is mainly used in people with type 2 diabetes to lower blood sugar levels. It’s also helpful in managing heart failure and chronic kidney disease, even in people without diabetes. It works by helping the body get rid of extra sugar through the urine.
Classification
Antidiabetic
Uses
Type 2 diabetes – to improve blood sugar control
Heart failure – to ease symptoms and reduce hospital visits
Chronic kidney disease – to protect kidney function and slow progression
Sometimes used to reduce the risk of heart-related complications
How It Works
Dapagliflozin blocks a protein in the kidneys (SGLT2) that usually reabsorbs sugar back into the body. By stopping this process, the medicine causes more sugar to pass out through urine, lowering blood sugar levels. This also helps the body get rid of extra fluid, easing the strain on the heart and kidneys.
Dosage
As prescribed by your doctor.
Side effects
Urinary tract infections
Increased urination
Genital infections (especially in women)
Low blood sugar (when used with insulin or other diabetes drugs)
Dehydration, which can lead to dizziness or lightheadedness
In rare cases, ketoacidosis (a serious condition involving high acid levels in the blood)
Precautions
Drink enough water to avoid dehydration, especially during hot weather or if you exercise.
Inform your doctor if you have kidney problems, liver disease, or a history of urinary tract infections.
Not usually recommended for people with type 1 diabetes.
Watch for symptoms like nausea, vomiting, stomach pain, or trouble breathing, and report them immediately (possible signs of ketoacidosis).
If you’re pregnant or breastfeeding, consult your doctor before starting this medicine.
Let your doctor know about all other medications you are taking.
Disclaimer
This content is for informational purposes only. Always consult a healthcare provider for medical advice and proper dosage
Vildagliptin
VILDAGLIPTIN
Overview:
Vildagliptin is a medication used to help manage blood sugar levels in people with type 2 diabetes. It’s usually taken along with diet, exercise, and sometimes other diabetes medicines. While it doesn’t cure diabetes, it helps keep your blood sugar in a healthier range, which lowers the risk of complications like nerve damage, kidney problems, and heart disease.
Classification:
Drug class: DPP-4 inhibitor (Dipeptidyl Peptidase-4 inhibitor)
Uses:
It is used to treat type 2 diabetes in adults
Often prescribed alone or with other medications like metformin, sulfonylureas, or insulin
Helps improve long-term blood sugar control when diet and exercise alone aren’t enough
How It Work:
Vildagliptin works by helping your pancreas release the right amount of insulin after you eat, and at the same time, it lowers the amount of sugar your liver makes. It does this by blocking an enzyme called DPP-4, which breaks down hormones that help control blood sugar. So basically, it helps your body respond better to meals and keeps your blood sugar levels more stable.
Dosage:
As prescribed by your doctor.
Side Effects:
Most people tolerate vildagliptin well, but some may experience:
Common side effects
Headache
Dizziness
Mild stomach discomfort or nausea
Cold-like symptoms (runny nose, sore throat)
Less Common side effects
Signs of liver problems (like yellowing of skin or eyes, dark urine)
Muscle pain or weakness
Allergic reactions (rash, itching, swelling)
If you’re taking vildagliptin with another diabetes medicine, especially insulin or sulfonylureas, it may increase your risk of low blood sugar (hypoglycemia). Watch for symptoms like shakiness, sweating, or feeling very hungry or irritable.
Precautions:
Liver function: Vildagliptin can sometimes affect the liver, so your doctor may check your liver enzymes regularly.
Kidney problems: Dose adjustments might be needed if you have kidney issues.
Pregnancy and breastfeeding: Not usually recommended unless clearly needed—talk to your doctor.
Alcohol: Be careful with alcohol, as it can affect blood sugar levels and liver function.
Tell your doctor about all medications and supplements you’re taking to avoid unwanted interactions
Disclaimer:
This content is for informational purposes only. Always consult a healthcare provider for medical advice and proper dosage
