What are you looking for?
DERMIFLOX Cream 15gm
No Prescription yet? Don’t worry! Click Here to Get Online Consultation
DERMIFLOX CREAM is a combination of Beclomethasone, Ketoconazole and Neomycin which belongs to the group of medicines called Corticosteroids, Antifungals and Antibiotics respectively. It is used for the topical management of bacterial and fungal skin infections with associated inflammation.
Ketoconazole
Ketoconazole – An Antifungal Medication
Ketoconazole is a synthetic, broad-spectrum antifungal medication used to treat a wide variety of fungal and yeast infections. It works by inhibiting ergosterol synthesis in the fungal cell membrane, thereby destroying the fungus at its source and preventing its growth.
Ketoconazole is available in multiple forms, including topical creams, medicated shampoos (commonly for dandruff and seborrheic dermatitis), and oral tablets for systemic infections.
Therapeutic Uses
Scalp Conditions: Effective in treating persistent dandruff and seborrheic dermatitis that are difficult to manage.
Skin Infections: Used for Athlete’s Foot (tinea pedis), Jock Itch (tinea cruris), and Ringworm (tinea corporis).
Pityriasis (Tinea Versicolor): Helps clear fungal patches causing skin discoloration.
Systemic Infections: Oral form is useful for deep or resistant fungal infections that do not respond to standard treatments.
How to Use
Topical Cream: Apply a thin layer to the clean, dry affected area once or twice daily. Wash hands thoroughly after application.
Shampoo: Apply to wet scalp/hair, lather, and leave for 3–5 minutes before rinsing. Typically used twice weekly for 2–4 weeks.
Oral Tablets: Take exactly as prescribed, preferably with food to enhance absorption.
Safety & Precautions
Caution: Avoid applying on broken or irritated skin. Keep away from eyes, nose, and mouth.
Liver Function: Monitoring of liver enzymes may be required with oral ketoconazole, due to rare risk of liver toxicity.
Alcohol: Avoid alcohol consumption during oral therapy to prevent adverse reactions.
Pregnancy & Breastfeeding: Consult a doctor or dermatologist before use.
Side Effects & Interactions
Generally well-tolerated, but some users may experience:
Local Effects: Mild redness, itching, or stinging.
Systemic Effects: Nausea, headache, abdominal discomfort (more common with oral form).
Drug Interactions: May interact with antacids and blood thinners. Always inform your pharmacist or doctor about current medications.
Frequently Asked Questions (FAQs)
Q: Can I apply ketoconazole cream to the scalp?
A: While primarily used for skin infections, it may help with scalp inflammation (e.g., related to androgenic alopecia) under medical supervision.
Q: How soon does it start working?
A: Initial improvement such as reduced itching and flaking is usually noticed after 2–3 applications.
Q: Can ketoconazole be used on the face?
A: Yes, for conditions like facial seborrheic dermatitis, but use only as directed and avoid the eye area.
Q: Can I stop using it once the rash disappears?
A: No. Continue for a few days after symptoms resolve to ensure complete eradication of the fungus and prevent recurrence.
Q: Can I use a moisturizer with ketoconazole cream?
A: Yes. Apply a moisturizer 20–30 minutes after using ketoconazole to maintain its effectiveness.
Neomycin
Neomycin Topical Sulfate (USP/IP)
Neomycin is a potent aminoglycoside antibiotic used to treat and prevent bacterial skin infections. It works by inhibiting bacterial protein synthesis, thereby stopping the growth and multiplication of bacteria. It is effective mainly against gram-negative and some gram-positive organisms, and is commonly included in “triple antibiotic” ointments for minor skin care.
Therapeutic Uses
Infected Minor Wounds: Prevents infection in cuts and abrasions
Minor Burns: Protects damaged skin from secondary bacterial infection
Secondary Skin Infections: Used in eczema or impetigo when infected
Pre-Surgical Prep: Helps in surface sterilization before minor procedures
Salient Features
Localized Action: Works directly at the site of infection
Rapid Effect: Begins acting on surface bacteria quickly
Multiple Forms: Available as creams, ointments, and powders
Usage
Preparation: Wash hands and clean area with soap and water
Application: Apply a thin layer to affected area
Frequency: Use 1–3 times daily as advised
Protection: Cover with a sterile bandage if required
Unwanted Side Effects and Safety
Mild redness or irritation
Itching or stinging sensation
Allergic Contact Dermatitis: rash or hives may occur
Warning: Avoid use on large open wounds due to risk of systemic absorption and rare ototoxicity or nephrotoxicity
Precautions and Warnings
Duration: Do not use beyond 7 days without medical advice
Sensitive Areas: Avoid use in eyes or ear canal
Pregnancy: Use under medical supervision
Pediatric Use: Generally safe for children above 2 years with guidance
Frequently Asked Questions
Q: Can it treat acne?
Not ideal; better options include benzoyl peroxide or clindamycin
Q: What if swallowed accidentally?
Usually causes mild stomach irritation; seek help if large amount ingested
Q: Why is my skin red and itchy?
Possible allergic reaction; discontinue use and consult a doctor
Q: Can it treat fungal infections?
No, it works only against bacterial infections
Q: Can it be used under a dressing?
Yes, but consult a doctor if the wound is severe or highly inflamed
At Gem Pharmacy, we make every effort to provide accurate, expert-written, and thoroughly reviewed information related to medicines. However, this information should not be considered a substitute for professional medical advice, diagnosis, or treatment from a qualified doctor.
The purpose of this information is to educate users and improve communication between patients and healthcare professionals. It should not be used to diagnose or treat any condition.
Always consult a certified healthcare professional before taking any medication.
Related products
Bold Care Ketoconazole and Zinc Pyrithione Anti Dandruff Shampoo
