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Aluminium Hydroxide Suspension / Tablets
Aluminium Hydroxide, an effective antacid and inorganic salt used for neutralizing excess gastric juice, is predominantly indicated in the symptomatic management of heartburn, acid indigestion, and sour stomach. Also, in patients suffering from chronic kidney diseases, it serves as a phosphate binder to normalize high phosphate levels in the blood by active phosphate binding in the digestive tract.
Indication
Neutralization Diagnosis: Provides immediate relief for gastritis, ulcer, and heartburn.
Godsend for Phosphate Balance: Highly prescribed for mineral imbalance in renal failure.
Diagnosis for chronic abdominal Problem: Conditions include bloating and discomfort in patients with hyperacidity.
Mechanism of Action
Aluminium Hydroxide acts on the stomach’s local environment, thereby stabilizing the equilibrium of acid to base in the stomach. Aluminium hydrate is able to neutralize gastric acidity because it reacts with the acid in the gastric juice (hydrochloric acid) to form aluminum chloride and water. This shifts the pH of the gastric contents upwards considerably, reducing the burning sensation of acidity while having little effect on the body’s overall acid–base status.
Dosage Form & Administration
Acidity: Between meals and at bedtime.
Phosphate: Must be swallowed with food to bind with phosphorus in food.
Liquid Form: Shake the bottle well before use. Use a graduated measuring cup to measure your dose.
Tablet Form: Chew the tablet completely before swallowing for faster activation in the stomach.
Safety Information & Interactions
Drug Spacing: Aluminium hydroxide increases other drugs’ decreased absorption (such as tetracyclines, digoxin, and iron supplements). These other medications are commonly dosed at least 2 hours before or after the antacids are taken.
Kidney: If you have kidney disease, use this drug with caution, as the aluminium can accumulate in your body.
Long Use Chronic Phosphate Levels: Long-term use can lead to decreased phosphate levels (hypophosphatemia) in your bloodstream, resulting in muscle weakness or bone pain.
A significant side effect profile is minimal, with a possibility of occasional constipation that can mostly be managed by increasing water or fiber intake. Some may experience chalky taste after consumption.
Frequently Asked Questions (FAQs)
Q: Can I take Aluminium Hydroxide every day?
It is safe for short-term relief of acidity. However, if you find yourself needing it for more than two weeks consecutively, consult a doctor to rule out underlying conditions like chronic ulcers.
Q: Why does it cause constipation, and how can I prevent it?
Aluminium salts naturally slow down bowel movements. Many commercial formulations combine Aluminium Hydroxide with Magnesium Hydroxide to balance this effect. To prevent constipation, stay hydrated and maintain a high-fiber diet.
Q: Is it safe during pregnancy?
Antacids are generally considered safe during pregnancy when used occasionally. However, you should always consult your OB-GYN before starting any medication while pregnant.
Q: Can I take this with fruit juice?
Avoid taking Aluminium Hydroxide with citrus juices (like orange or lemon juice). Citric acid can significantly increase the absorption of aluminium into your bloodstream, which may be harmful over long periods.
Q: How soon will I feel relief?
For heartburn or indigestion, you should feel a reduction in symptoms within 15 to 30 minutes after consumption.
