GASOWEL Orange Flavour Effervescent Tablet 2’s

Diastase

Fungal Diastase

Digestive Enzyme / Nutritional Supplement

Aristozyme, Digeplex, Vitazyme.

Oral Liquid (Syrup), Capsules, Tablets

Highlights

Diastase, also known as Fungal Diastase, is a very potent digestive enzyme that helps the body break down complex carbohydrates and starches into simpler sugars. The enzyme is normally derived from Aspergillus oryzae and acts effectively to reduce indigestion and gastric distress. It is commonly prescribed along with Pepsin to provide a dual-action digestive support for both protein and carbohydrate digestion.

Specific Benefits and Uses

Indigestion: This preparation helps relieve a feeling of heaviness in the stomach, flatulence, and bloating after meals.

Starches: Through hydrolysis facilitated by diastase, starch is converted into maltose, thereby reducing the workload on the pancreas.

Disease Support: Often recommended for patients with functional dyspepsia or individuals recovering from chronic illness where digestive function may be weak.

Appetite Enhancement: By improving gastric digestion, diastase helps restore natural appetite in both children and adults.

Dosing Diastase

Dosage: Adults usually require 5–10 ml (1–2 teaspoons) twice daily, or as prescribed by a doctor.

Timing: Diastase should be taken immediately after meals for maximum effectiveness. Taking it without food may reduce its digestive action.

Consistency: The medicine should be taken at the same time every day to help maintain consistent digestive support.

Safety Precautions and Interactions

Allergenic: Do not use if you are allergic to fungal diastase or any inactive ingredients in the syrup. Always consult your physician if you suspect an allergy.

Chronic Diseases: Individuals with pancreatitis, diabetes (due to sugar content in the syrup), or persistent abdominal pain should consult a doctor before using.

Side Effects: Some individuals may experience mild nausea, diarrhea, or stomach cramps. If symptoms persist or worsen, medical advice should be sought.

Pregnancy/Nursing: Medical consultation is recommended before using this product during pregnancy or breastfeeding.

Frequently Asked Questions (FAQs)

1. What exactly is Diastase?
Diastase refers to a group of enzymes that break down starch into maltose. In pharmacology, it is widely used as a digestive aid to help digest heavy or starch-rich meals.

2. Can Diastase cure chronic acidity?
Diastase may help relieve indigestion and bloating associated with acidity, but it does not treat GERD (acid reflux). It works by improving digestion rather than suppressing stomach acid.

3. Is Fungal Diastase safe for kids?
Yes, it is often prescribed in lower doses for children, especially for loss of appetite or digestive discomfort. A pediatrician should determine the correct dose based on the child’s age and weight.

4. Can Diastase be taken with other medications?
Generally yes, but it is recommended to avoid taking it simultaneously with certain antacids, as they may interfere with enzyme activity. Always inform your doctor about all medications you are currently taking.

5. How should I store the syrup?
Store the product in a cool, dry place away from direct sunlight. Do not freeze the bottle and ensure the cap is tightly closed after each use to prevent contamination.

Papain

Papain is a proteolytic enzyme extracted from the fruit of the papaya plant (Carica papaya). It is widely used as a digestive aid, helping break down complex proteins into simpler peptides and amino acids. Clinically, it is also recognized for its role in wound healing and as a potent anti-inflammatory agent.

Benefits to Primary Health

Optimizes the Digestion: Helps reduce bloating by breaking down high-protein meals efficiently.

Prevents Bloating and Gas: Limits fermentation in the stomach, thereby reducing gas formation.

Anti-Inflammatory: Helps reduce swelling and pain, especially after dental procedures or minor injuries.

Immune Support: Acts as a potent antioxidant, combating oxidative stress.

Sore Throat Relief: Lozenges may help reduce redness and swelling of the throat and pharynx.

Usage of Papain

For Digestion: Most effective when taken during or immediately after meals.

Dosage: Typically available in 100 to 500 mg capsules or chewable tablets. Always follow package instructions or your nutritionist’s advice.

Administration: Chewable tablets should be fully chewed or dissolved before swallowing for maximum enzyme activity in the mouth and throat.

Safety Precautions & Warnings

Allergy Alert: Individuals allergic to latex may experience cross-reactivity with papain (also linked with kiwi or figs). Discontinue use if rash or itching occurs.

Pregnancy & Breastfeeding: Generally not recommended during pregnancy, as enzymes from unripe papaya may trigger uterine contractions.

Surgical Precaution: Stop use at least 2 weeks before surgery or dental procedures due to its mild blood-thinning effect.

Drug Interaction: Consult a doctor before combining with blood thinners like Warfarin, as it may increase bruising risk.

Potential Side Effects

Papain is generally well-tolerated, but some users may experience:

• Mild stomach cramps
• Temporary diarrhea (especially at high doses)
• Throat irritation (with strong lozenges)

Frequently Asked Questions (FAQs)

Q: Can I mix the labels for Papain and Bromelain?
A: Both are proteolytic enzymes, but differ in source and function. Papain (from papaya) is more focused on protein digestion, while Bromelain (from pineapple) is often used for joint inflammation.

Q: Will taking Papain with water make me thin?
A: Papain is not a fat burner, but it may improve digestion and reduce bloating, which can contribute to a flatter abdomen.

Q: So will Morphin affect Papain in some way?
A: Some proteolytic enzymes may enhance the absorption of certain medications. It’s best to space doses or consult your healthcare provider.

Q: Can I get enough Papain from merely having the ripe papaya fruit?
A: Ripe papaya is beneficial, but higher concentrations of papain are found in unripe (green) papaya latex. Supplements provide a more standardized dose.

Q: Is it safe for daily use?
A: Generally safe for healthy adults when used as directed. For chronic conditions, cyclic use under professional guidance is recommended.

Simethicone

Simethicone, often prescribed as oral drops, chewable tablets, or capsules to relieve gas and pain, has almost become an accepted default anti-foaming agent for dyspepsia. Simethicone is actually an inert material that works to relieve its issues in physical ways without entering the general circulation and hence it is safe enough for children. Simethicone is usually available singly or in a tablet combined with an antacid for indigestion and heartburn.

UseTherapeutic Uses
Relieves Bloating: Quickly eases the bloated sensation of fullness and pressure in the stomach
Manages Flatulence: Assists in easy escape of the air, thereby reducing trapping of intestinal wind
Infantile Colic: Pediatric drops are often used to soothe babies with gas-induced distress
Preparation for Diagnosis: Occasionally used to clear out the gas shadow from the gastrointestinal tract before endoscopic or radiographic investigations

Mechanism of Action
All in all, simethicone lowers the surface tension of gas bubbles in the stomach and intestines.
Coalescence: This phenomenon brings together the small bubbles caught inside the larger ones.
Evacuation: These larger bubbles become more manageable for the body to excrete either by belching or burping.
Note: Simethicone does not prevent gas from forming but makes it easier to exit from the body.

Dosage & Administration
Adults: Generally, 40-125 mg should be taken four times a day or the dosage should be given as needed.
Children: Dosage used in infants is normally weight-based. Use the medicine dropper provided with the drug.
Timing: It is better to take simethicone after meals and at bedtime.
Form: The chewable tablets need to be thoroughly chewed before swallowing; liquids must be shaken prior to usage

Safety Profile & Side Effects
Since simethicone does not enter the bloodstream, its side effects are almost nonexistent, leading to a good safety profile.
Use of Common Side Effects: Infrequent record of diarrhea or nausea. Consult your physician if you experience any signs of allergy.

Prep & Warnings
Interactions: Simethicone could potentially reduce the uptake of indifferent thyroid medicaments (Levothyroxine) while being taken. Keep four hours in between the two.
Pregnancy/Breastfeeding: It ought to be fine, as it is not leaked into the general circulation, but do ask the doctor.
Underlying/Minor Ailments: If they bother people for more than two weeks or get worse, sidle close to a gastroenterologist.

FAQs
Q: Can Simethicone be an antacid?
No; simethicone is, in fact, an antiflatulent. While the combination of antacids and simethicone (such as magnesium hydroxide) available sell them as "2-in-1," they do not, in fact, work to neutralize stomach acid. It is working to break down the gas bubbles.

Q: When does simethicone usually begin to work?
You will typically feel relief in 15 to 30 minutes, as the gas bubbles begin to move through and break up in the digestive tract.

Q: Can I give simethicone to my newborn?
Yes, actually simethicone is quite often given to colicky babies. Just make sure you use only the infant-strength (drops) and administer as per pediatrician's instructions.

Q: Can simethicone be taken every day?
You can use it daily as needed; however, always discuss with your doctor if you need it every day for more than two weeks, to rule out chronic conditions like IBS or food intolerances.

Q: Does simethicone cause constipation?
No, simethicone doesn't usually induce constipation. Should you experience an alteration of your bowel habits, it could be the other ingredients and/or any existing components present within the formula that promote bowel habit alterations, so talk with your doctor about simethicone or the composition of the pharmaceutical preparation.

Storage
Store at room temperature ($20\text{°C}$ to $25\text{°C}$). Keep bottled products away from dampness and heat. Always keep the bottle tightly closed when not in use.

Disclaimer: These facts are only for educational purposes and not a piece of actual medical advice. Always go through the label or see your physician before using the product.