Mahaketo 5 RF Cream

Beclomethasone Dipropionate

Beclomethasone dipropionate (Topical/Inhalational)

Beclomethasone Dipropionate is a potent corticosteroid used to reduce inflammation, redness, and itching. Depending on its formulation (cream, ointment, or inhaler), it works by suppressing the immune response and decreasing the release of inflammatory substances. It is widely used in asthma, allergic rhinitis, and skin conditions like eczema and psoriasis.

Therapeutic Uses

Prevention of asthma symptoms such as wheezing and breathlessness

Reduction of skin inflammation, redness, and itching

Management of allergic rhinitis and nasal congestion

Treatment of nasal polyps by reducing their size

How It Works

Beclomethasone Dipropionate is a prodrug that becomes active after conversion in the body. It blocks prostaglandins and leukotrienes, which are responsible for inflammation flare-ups in the lungs and skin.

How to Use

Inhalers: Use at the same time daily; rinse mouth after use to prevent oral thrush

Topical Application: Apply a thin layer; avoid covering with bandages

Consistency: Take regularly as prescribed; effects may take 3–7 days

Advice on Safety and Precautions

Pregnancy/Lactation: Use only under medical advice

Infected Skin: Avoid use on untreated infections

Eye Contact: Do not apply near eyes due to risk of glaucoma or cataracts

Children: Requires growth monitoring during long-term use

Side Effects

Inhalation: Hoarseness, sore throat, or oral thrush

Topical: Skin thinning, stretch marks, or burning sensation

Nasal: Dryness or nosebleeds

Frequently Asked Questions

Q: Can it be used during an asthma attack?
No, it is a preventer, not a rescue inhaler (use salbutamol instead)

Q: Why rinse mouth after inhaler use?
To prevent oral infections and hoarseness

Q: Is it safe for the face?
Only under dermatologist supervision for short duration

Q: What if I miss a dose?
Take it when remembered; do not double dose

Q: Does it cause weight gain?
Unlikely, as systemic absorption is minimal compared to oral steroids

Ketoconazole

Ketoconazole – An Antifungal Medication

Ketoconazole is a synthetic, broad-spectrum antifungal medication used to treat a wide variety of fungal and yeast infections. It works by inhibiting ergosterol synthesis in the fungal cell membrane, thereby destroying the fungus at its source and preventing its growth.

Ketoconazole is available in multiple forms, including topical creams, medicated shampoos (commonly for dandruff and seborrheic dermatitis), and oral tablets for systemic infections.

Therapeutic Uses

Scalp Conditions: Effective in treating persistent dandruff and seborrheic dermatitis that are difficult to manage.

Skin Infections: Used for Athlete’s Foot (tinea pedis), Jock Itch (tinea cruris), and Ringworm (tinea corporis).

Pityriasis (Tinea Versicolor): Helps clear fungal patches causing skin discoloration.

Systemic Infections: Oral form is useful for deep or resistant fungal infections that do not respond to standard treatments.

How to Use

Topical Cream: Apply a thin layer to the clean, dry affected area once or twice daily. Wash hands thoroughly after application.

Shampoo: Apply to wet scalp/hair, lather, and leave for 3–5 minutes before rinsing. Typically used twice weekly for 2–4 weeks.

Oral Tablets: Take exactly as prescribed, preferably with food to enhance absorption.

Safety & Precautions

Caution: Avoid applying on broken or irritated skin. Keep away from eyes, nose, and mouth.

Liver Function: Monitoring of liver enzymes may be required with oral ketoconazole, due to rare risk of liver toxicity.

Alcohol: Avoid alcohol consumption during oral therapy to prevent adverse reactions.

Pregnancy & Breastfeeding: Consult a doctor or dermatologist before use.

Side Effects & Interactions

Generally well-tolerated, but some users may experience:

Local Effects: Mild redness, itching, or stinging.

Systemic Effects: Nausea, headache, abdominal discomfort (more common with oral form).

Drug Interactions: May interact with antacids and blood thinners. Always inform your pharmacist or doctor about current medications.

Frequently Asked Questions (FAQs)

Q: Can I apply ketoconazole cream to the scalp?
A: While primarily used for skin infections, it may help with scalp inflammation (e.g., related to androgenic alopecia) under medical supervision.

Q: How soon does it start working?
A: Initial improvement such as reduced itching and flaking is usually noticed after 2–3 applications.

Q: Can ketoconazole be used on the face?
A: Yes, for conditions like facial seborrheic dermatitis, but use only as directed and avoid the eye area.

Q: Can I stop using it once the rash disappears?
A: No. Continue for a few days after symptoms resolve to ensure complete eradication of the fungus and prevent recurrence.

Q: Can I use a moisturizer with ketoconazole cream?
A: Yes. Apply a moisturizer 20–30 minutes after using ketoconazole to maintain its effectiveness.

Neomycin

Neomycin Topical Sulfate (USP/IP)

Neomycin is a potent aminoglycoside antibiotic used to treat and prevent bacterial skin infections. It works by inhibiting bacterial protein synthesis, thereby stopping the growth and multiplication of bacteria. It is effective mainly against gram-negative and some gram-positive organisms, and is commonly included in “triple antibiotic” ointments for minor skin care.

Therapeutic Uses

Infected Minor Wounds: Prevents infection in cuts and abrasions

Minor Burns: Protects damaged skin from secondary bacterial infection

Secondary Skin Infections: Used in eczema or impetigo when infected

Pre-Surgical Prep: Helps in surface sterilization before minor procedures

Salient Features

Localized Action: Works directly at the site of infection

Rapid Effect: Begins acting on surface bacteria quickly

Multiple Forms: Available as creams, ointments, and powders

Usage

Preparation: Wash hands and clean area with soap and water

Application: Apply a thin layer to affected area

Frequency: Use 1–3 times daily as advised

Protection: Cover with a sterile bandage if required

Unwanted Side Effects and Safety

Mild redness or irritation

Itching or stinging sensation

Allergic Contact Dermatitis: rash or hives may occur

Warning: Avoid use on large open wounds due to risk of systemic absorption and rare ototoxicity or nephrotoxicity

Precautions and Warnings

Duration: Do not use beyond 7 days without medical advice

Sensitive Areas: Avoid use in eyes or ear canal

Pregnancy: Use under medical supervision

Pediatric Use: Generally safe for children above 2 years with guidance

Frequently Asked Questions

Q: Can it treat acne?
Not ideal; better options include benzoyl peroxide or clindamycin

Q: What if swallowed accidentally?
Usually causes mild stomach irritation; seek help if large amount ingested

Q: Why is my skin red and itchy?
Possible allergic reaction; discontinue use and consult a doctor

Q: Can it treat fungal infections?
No, it works only against bacterial infections

Q: Can it be used under a dressing?
Yes, but consult a doctor if the wound is severe or highly inflamed