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Alpha-ketoanalogue supports compromised renal functions typically having a profound influence on patients who have already reached a significantly diminished Glomerular Filtration Rate (GFR) of 25 ml per minute. It aims at hindering the progression of renal failure and delaying the time when dialysis readings are needed.
This provides the fundamental principle contrary to the standard dietary protein source by “anabolic use” (protein synthesis) of essential amino acids (“keto” or “hydroxy” forms), and hence the synthesis of toxic nitrogenous waste products (for example, urea) with respect to those kidneys that are unable to filter.
Main Points
· Preserves renal function: Reduces metabolic load upon kidneys and delays the onset of chronic kidney diseases upon them.
· Renal function helps reduce metabolic uremic toxins: This will help reduce the accumulation of uremic toxins and other nitrogenous waste products in the blood.
· Provides nutritional support: Prevents protein-energy malnutrition in patients on a strict low-protein diet.
*Delays Dialysis-*The clinical evidence suggests postponing the initiation of regular dialysis, thereby helping the management of nutrition.
Product Overview
The Alpha-Ketoanalogue belongs to the class of amino acid supplements used in urology. It traverses the metabolic pathways commonly associated with essential amino acids. Ketoanalogues combine with non-essential amino acids in the body to draw nitrogen from them and to imitate the essential amino acid. The particular “recycling” process is in full control of the nitrogenous wastes in the body while it provides the necessary protein blocks.
Therapeutic Content
Metabolic Balance: Corrects the deficiency in protein metabolism arising from the deteriorating kidney functions.
Relief from Symptoms: May help reduce the symptoms associated with uremia, such as fatigue, nausea, and loss of appetite.
Muscle Maintenance: Helps to build up and repair muscle tissue, thus preventing muscle wasting as commonly seen in patients with chronic disease.
It functions best with the following: a low-protein or very-low protein diet as described by the nephrologist.
Ingredients
Each film-coated tablet contains following amounts of ingredients:
Calcium Keto-Leucine
Calcium Keto-Isoleucine
Calcium Keto-Phenylalanine
Calcium Keto-Valine
Calcium Hydroxy-Methionine
Essential amino acids: Lysine, Threonine, Tryptophan, Histidine, and Tyrosine
Directions For Use
How to use: Tablets should be swallowed whole, if necessary, water, with or without meals. This timing will help them acquire better amino acids.
Standard Dosage: Dosage is generally calculated in four to five kg of body weight per tablet and three times daily.
Important Information: Always complete the recommended dosage, usually depending on your weight as per the prescription. Do not crush or chew.
Patient Safety And Precautions
Allergy: Do not use if you are allergic to any of the components.
Hypercalcemia: This supplement contains calcium salts. Hence, this is not advised for the people having high levels of blood calcium.
Monitoring: Regular routine blood-testing should be carried out by him about serum levels of calcium and phosphorus.
Drug Interactions: May interact with certain antibiotics (like tetracyclines or quinolones) and iron supplements. Keep at least a 2-hour gap between the regular consumption of one and the other.
Pregnancy/Nursing: Pregnant women must consult their physician. A woman planning a baby should also take this advice into consideration. And likewise for breastfeeding.
FAQs
Q: What is the main use of Alpha Ketoanalogue?
A: Nutritional therapy is essentially for the prevention and treatment of medical issues related to protein metabolism disorders among patients with chronic renal failure.
Q: Can I take this medicine with my regular diet?
A: Its intake with a low-protein diet will likely ensure the best results. This is the shape in which the drug ensures reduced nitrogenous burden on your kidneys.
Q: Will there be any side-effects that are not common?
A: The most common side effects are hypercalcemia. This is due to the increased amount of calcium in the blood. Some patients may also experience mild nausea or indigestion.
Q: How long do I have to take this supplement?
A: CKD is always a long-term disorder—you should just keep up the medication until your doctor advises stopping it. Do not immediately stop taking the treatment.
Q: Is this safe for diabetic patients?
A: Diabetic nephropathy patients are prescribed this supplement mainly to slow the progression of kidney damage. This should only be with medical caution.
